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Lamotrigine
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Lamotrigine

Lamotrigine was originally developed as an antiseizure drug because of its ability to reduce folate levels. At the time of the drug's development, it was thought that folate depletion would treat epileptic activity. Although this is now known to be incorrect, the drug did serendipitously treat seizures effectively. Currently, pharmacologists understand that Lamotrigine reduces neuronal activity via a variety of mechanisms. The most commonly accepted mechanisms of action are enhancement of sodium channel inactivation and possible inhibition of synaptic glutamate release. In early studies, patients with epilepsy who were taking Lamotrigine reported increases in a subjective sense of well-being, and this led to its exploration as a psychotropic drug. From a neuropsychiatric standpoint, Lamotrigine appears to inhibit uptake of serotonin, dopamine, and noradrenaline.

Other names for this medication:
Lamotrigine, Lamictal, Daksol, Epitec, Flamus, Labileno, Lafigin, Lamal, Lambipol, Lamez, Lamictin, Lamidus, Lamirax, Lamitor, Lamitrin, Lamogine, Lamolep, Lamotrigin, Lamotrigina, Lamotrix, Lomarin, Meganox,

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Lamotrigine is a medicine used to treat epilepsy.

It can also help prevent low mood (depression) in adults with bipolar disorder.

Lamotrigine is available on prescription. It comes as tablets that you can either chew or dissolve in water to make a drink.

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MMP11 vaccine induced cell mediated and antibody immune response and exerted significant antitumoral protection in mice with colon cancer in prophylactic and therapeutic settings. From May 2008 to April 2009, 62 pregnant women who underwent elective cesarean section in the Department of Obstetrics, Affiliated Hospital of Qingdao University Medical College, were recruited, including 32 with GDM (GDM group) and 30 with normal glucose tolerance test (control group). H-reflexes can be reliably used in longitudinal studies to investigate mechanisms of recovery post-SCI. A preliminary study on the therapeutic effects of a calcium antagonist (diltiazem) on primary congestive cardiomyopathy. A case-control study of dietary salt intake in pediatric-onset multiple sclerosis.

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The aim of this study was to generate a human scFv-phage library from lymph nodes of patients with breast cancer and to develop a stringent depletion and selection protocol in order to isolate specific single chain antibodies recognizing potentially new antigens in breast cancer. While GERD is most commonly seen in Western populations, changes in dietary patterns and the global increase in obesity have led to a pronounced increase in its prevalence worldwide. The present study provides a molecular basis for the identity of human ES cells and demonstrates that during their in vitro differentiation they express embryonic specific genes in a stage specific manner.

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Current clinical presentation and treatment of localized prostate cancer in the United States. We report a case of primary amyloidosis with pleural effusion and suggest that pleural involvement and pleural effusion be added to the classification of pulmonary amyloidosis, and that amyloidosis be added to the list of causes of a pleural effusion. Unfortunately, transplant patients often have a low vitamin D concentration, which has well-known effects on calcium and bone metabolism. We report the first known case of a fatal sting by the large carpenter bee, Xylocopa tranquebarica, in a forested area in Puttalam (North Western Province) in the dry zone of Sri Lanka.

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