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Topimax (Topiramate)

Topimax is a broad spectrum, antiepileptic drug used for various types of seizures, Lennox-Gastaut syndrome (a type of childhood onset epilepsy), and migraine prophylaxis. Topimax blocks voltage-dependent sodium channels, potentiates gamma-aminobutyric acid (GABA) activity at some of the GABA receptors, and inhibits potentiation of the glutamate receptor and carbonic anhydrase enzyme, which all contribute to its antiepileptic and antimigraine efficacy.

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

Similar Products:
Epitomax, Diclox, Repaglinida, Avecor, Sevikar, Clavam, Corbis, Glumetza, Sulotrim, Tramacip, Uprox, Dilantin, Valium, Clonotril, Claxy, Volero, Norsic, Ranomax, Esmolol, Stomorgyl, Effigel, Altiva, Avir, Moxatag, Clarithromycin, Tolbin, Tussamag, Lipibec, Sofab, Medibiox, Lanzostad, Cardyn, Repa, Sepram, Epifenac, Saphire, Lansohexal, Anadir, Amvasc, Tenaron, Recamicina, Xergic, Levoquinol, Carca, Selegos, Paine,

Topimax is used alone or together with other medicines to help treat certain types of seizures (eg, partial seizures, tonic-clonic seizures, or Lennox-Gastaut syndrome). This medicine will not cure epilepsy and will only work to control seizures for as long as you continue to take it. It is also used to help prevent migraine headaches.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Capsule, Extended Release
  • Tablet
  • Capsule

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The studies exhibit a remarkably consistent pattern for the frequency distribution of IOP. The top of the domes are ground and polished to produce flat surfaces of prescribed depths relative to shell thickness. Early diagnosis, prompt initiation of antimicrobial therapy, and surgical drainage are essential to reduce morbidity and mortality. Lymphatic vessels and high endothelial venules are increased in the sentinel lymph nodes of patients with oral squamous cell carcinoma before the arrival of tumor cells.

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The patient developed Catastrophic Antiphospholipid Syndrome, probably due to infectious process and, antithrombotic therapy suppression because upper gastrointestinal bleeding, and dead. Potential neuroprotective drugs in cerebral ischemia: new saturated and polyunsaturated lipids coupled to hydrophilic moieties: synthesis and biological activity.

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Clinicopathologic features of ovarian neoplasms with emphasis on borderline ovarian tumors: an institutional perspective. As a solution to all problems, we advocate the use of both electrical basis functions (orthogonal prolate spheroidal basis functions) and optical basis functions, implemented as FBGs with orthogonal impulse response in addition to spatial modes.

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Sublingual immunotherapy (SLIT) appears to be acceptably safe in clinical trials, but post-marketing data are needed to provide essential information. Strategies to reduce cases of recurrent mastitis have to include improved treatment concepts and measures to decrease new infection rates.

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Evaluation of the Bio-Rad Geenius HIV-1/2 test as a confirmatory assay. Greater experience and refinements in surgical technique have improved the outcome for patients with risk factors limited to the first group. A comparable study were carried out by determination of trace elements on five marine-derived shell traditional Chinese medicine (TCM) (Ostreae Concha, Haliotidis Concha, Margaritifera Concha, Meretricis Concha, and Arcae Concha), which were recorded in the Chinese Pharmacopoeia (2010 version). Levels of NICD, Hes1, and Shh were increased in the SVZ at 4 and 24 h after focal cerebral ischemia.

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The potential role of ADAMs as key modulators of tumor-stroma interactions during tumor progression, by means of the activities of their constituent domains, is also discussed. This can provide information to identify lead candidates for further drug design and development. Coordinated DNA dynamics during the human telomerase catalytic cycle.

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Gas removal was performed from inside the breathing system at the same rate as that of the fresh gas inflow by means of an ejector flow-meter. The 5-HT2c receptor component of sertindole may be clinically relevant as this receptor subtype is implicated in regulation of anxiety, cognition/memory and brain plasticity. Proboscis lateralis is a very rare congenital malformation with heminasal hypoplasia or aplasia. We evaluated a risk-stratified prophylaxis protocol for patients undergoing TJA. The remodeling complexes SWI/SNF and ACF are unable to mobilize the variant H2ABbd nucleosome.

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At present, the ultrasonic diagnosis employs A, M and B-echograpic apparatus along with Doppler indicators and meters. EARLY DIAGNOSIS OF STOMACH CANCER BY ENDOSCOPY WITH SPECIAL REFERENCE TO FIBERGLASS GASTROSCOPY

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Three patients are observed in which division of the anterior and posterior superficial branches of the GAN during parotidectomy were complicated by self-inflicted injury. Retrograde horseradish peroxidase in conjunction with dimethyl sulfoxide was employed to flood the neonatal rat hypoglossal neuronal somata as well as their proximal and distal dendritic segments. The aim of the present study was to evaluate the effects of EE on ethanol-induced behavioral sensitization and BDNF expression.

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Interleukin-6 (IL-6) induces Pim1 expression and is often found elevated after androgen-ablative therapy. A European multi-center trial investigating the anti-restenotic effect of intravascular sonotherapy after stenting of de novo lesions (EUROSPAH: EUROpean Sonotherapy Prevention of Arterial Hyperplasia). Evidence for decreased expression of APPL1 associated with reduced insulin and adiponectin receptors expression in PCOS patients.

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The evaluation of these markers may influence the specific pharmacologic responses and the clinical outcome of the patients with essential hypertension. The future of orthodontic anchorage implants may well belong to micro-implants, developed in varying designs, lengths and diameters by different manufacturers. DHA-S levels in serum from 50 men and 86 women were in agreement with those in the literature.

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Products with low UVA protection have a lower capacity of preventing induced pigmentation compared with their efficacy against erythema. Strain-specific differences in susceptibility to mouse adenovirus type 1 (MAV-1) are linked to the quantitative trait locus Msq1 on mouse chromosome 15. In 1 of these 4 dogs, the right renal artery was gradually compressed and finally occluded. AMCase activity was measured in tears and AMCase mRNA expression was evaluated by real-time polymerase chain reaction from RNA extracted from epithelial cells of the conjunctiva.

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Next, we identified T cells as the direct target cells of the immunopotentiating LAB strain L32, suggesting that L32 induced antibody production by PBMCs through T-cell activation. Black physicians and the struggle for civil rights: lessons from the Mississippi experience: part 1: the forces for and against change.

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The clinical picture of affected individuals is highly dependent on the tissue of origin, and the presence or absence of functional hormone secretions. DNA elements are asymmetrically joined during the site-specific recombination of kappa immunoglobulin genes. The aim of this study was to investigate time course of procalcitonin (PCT), C-reactive protein (CRP) and white blood cell (WBC) levels in patients with therapeutic hypothermia after cardiac arrest. Neurons are highly vulnerable to ischemic/hypoxic stress, while glial cells show tolerance to such stress.

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Psychic trauma in children: observations following the Chowchilla school-bus kidnapping. We present the case of a 28-year-old female Rett syndrome patient with low bone mass and a recent fracture who was successfully treated with teriparatide. Moreover, no pathogens were found, neither using the non-specific 16S rRNA primers nor in routine quarterly health monitoring. A Stochastic Differential Equation Model for the Spread of HIV amongst People Who Inject Drugs. Individuals were also assessed for performance status using the Eastern Cooperative Oncology Group scale.

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Damage and recovery of bone marrow haemopoietic cells during and after continuous irradiation. These include the neurokinins, glutamate, purinoceptors, opioids and trophic factors. Often these individuals served as wise mentors who saw the need for further subspecialization in pediatrics and encouraged the development of academic careers that have resulted in advancing care for infants, children, and adolescents. Although great efforts were made to prolong the fertility of liquid-stored semen, limited improvements have been achieved in different species. Moreover, exogenous LacCer recovered the reduced expression of RANK and the phosphorylation of inhibitor of NF-kappa B and extracellular signal-regulated kinase 1/2 after stimulation by RANKL at the same level of cells without D-PDMP treatment.

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However, in CVF-transgenic mice, no infiltration of neutrophils, which were the prominent infiltrating cells at the site of infection in normal susceptible mice, could be detected. Observation of linear and quadratic magnetic field-dependence of magneto-photocurrents in InAs/GaSb superlattice. Despite wild-type binding to the cell surface, the resulting virions were noninfectious. the findings of this study suggest that fetuses exposed to misoprostol tend to be at higher risk of developing congenital malformations in comparison to non-exposed fetuses. Given that general proteasome inhibitors are currently used as anticancer agents, a better understanding of the ubiquitylation of specific targets by specific ubiquitin ligases may result in improved cancer therapeutics.

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Has this led to an improvement in the quality and quantity of publications related to radiotherapy? Zebrafish in Brazilian Science: Scientific Production, Impact, and Collaboration. These results suggest that supplementation with LUT could help to reduce symptoms of visual fatigue.

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Successful stopping was associated with activation of the right inferior frontal gyrus, as well as the pre-SMA. Engineering of pentose transport in Corynebacterium glutamicum to improve simultaneous utilization of mixed sugars. Two different biodegradation tests, one in compost environment, the other at aquatic conditions and additional compost analysis after degradation of the polymer have been done.

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Judgments of flicker intensity between pairs of colors were analyzed with multidimensional scaling (MDS)--in effect treating them as an index of color dissimilarity. A large increase in the demand for seafood products has occurred in the last century.

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Secondary structure of the human growth hormone releasing factor (GRF 1-29) by two-dimensional 1H-nmr spectroscopy. Classical breeding experiments have shown that wing pattern variation in this polymorphic Batesian mimic is determined by the polyallelic H locus that controls a set of distinct mimetic phenotypes.

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Oral sildenafil citrate as an effective alternate in the treatment of postoperative pulmonary hypertensive crisis after congenital heart surgery Prognostic significance of p27Kip1, Ki-67, and CRTC1-MAML2 fusion transcript in mucoepidermoid carcinoma: a molecular and clinicopathologic study of 101 cases. Human protein phosphatase 5 dissociates from heat-shock proteins and is proteolytically activated in response to arachidonic acid and the microtubule-depolymerizing drug nocodazole.

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The accumulation and microdistribution of uranium in the bone and marrow of Beagle dogs were determined by both neutron activation and neutron-fission analysis. Comparison of arthroplasties with or without bone tunnel creation for thumb basal joint arthritis: a randomized controlled trial.

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In addition, when subjected to prolonged incubation in the confluent state, fibroblast cultures will consistently withstand frozen storage and, upon thawing, will yield actively growing cultures, biochemically and morphologically indistinguishable from the cultures that were frozen. Radiation carcinogenesis is a stochastic phenomenon that does not exhibit any threshold in the dose-response relationship. The findings support the efficacy of some psychosocial interventions in people with CVDs. Congestive heart failure is very frequently associated with anaemia, iron deficiency and renal failure. One hundred five partially edentulous patients (77 males, 28 females, mean age: 46 years, range: 26-67 years) seeking oral implant rehabilitation were referred for presurgical imaging.

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OBJECTIVE To evaluate heart rate, heart rate variability, and arrhythmia frequency as well as changes in cardiac biomarker values and their association with heart rate in horses before and after an endurance ride. Our data suggest that loss of proliferative capacity in oxidatively stressed cells is a multistep process regulated by time-dependent molecular events that may play differential roles in induction and maintenance of cellular senescence.

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Further novel amido sugars within the glycopeptidolipid antigens of Mycobacterium avium. Blood samples and subcutaneous abdominal fat biopsies were collected from 12 T2D patients, of which 11 concluded the study, pre-treatment and 90 days after initiation of rosiglitazone treatment, and from 19 healthy control subjects on the first and only visit from healthy subjects. LincRNA-ROR induces epithelial-to-mesenchymal transition and contributes to breast cancer tumorigenesis and metastasis. The expression of aldolase A and B isoenzyme transcripts was confirmed by RT-PCR in rat kidney and their cell distribution was compared with characteristic enzymes of the gluconeogenic and glycolytic metabolic pathway: fructose-1,6-bisphosphatase (FBPase), phosphoenol pyruvate carboxykinase (PEPCK), and pyruvate kinase (PK).

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In our study of nonsmoking women, the LUMA methylation level in peripheral blood was not associated with the risk of lung cancer. Cyst formation was associated with an increase in cell proliferation and apoptosis. Effects of mumps outbreak in hospital, Chicago, Illinois, USA, 2006.

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This paper compares driver behaviour towards two novel warning devices (rumble strips and in-vehicle audio warning) with two conventional warning devices (flashing light and stop sign) at railway level crossings using microsimulation modelling. Older persons reporting disability are more likely to report poor self-rated health, but little work has been done to assess the independent relationships of reported walking difficulty and measured walking performance with self-rated health. Reproductive tract infections in pregnant women in Delhi, India. The success of antisense strategies has been limited by the poor uptake of the transfection reagent and inadequate intracellular compartmentalization.

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The neuroblasts begin to aggregate at 4.5 days around the aortic arch arteries and truncus arteriosus. NK activity of 60-79-year-old females was in a similar range of values as that of young females (20-35 years) and was lower than that of the males of the corresponding age groups.

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Displacement injuries of permanent teeth are an increasing emergency in the dental office. A compensatory response in deiodinase activity was only observed at day 8. The field representation in the core is based on the Lanczos-Fourier sinusoidal series. A high UF rate during HD is associated with a biochemical evidence of myocardial injury.

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We have previously described an anti-human neutrophil, murine monoclonal antibody PMN7C3, which specifically inhibits the respiratory burst of neutrophils stimulated with serum-opsonized yeast. With forced-choice methods using famous faces paired with unknown faces, no patient demonstrated covert familiarity.

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Eleven patients with tracheal stenosis or tracheal injury were managed with the silicone T-tube prosthesis from 1995 to 1999. Two highly aggressive and invasive cell lines, SW620 and COLO-320DM were the most sensitive to SIN infection. Relationship of dental diseases with coronary artery diseases and diabetes in Bangladesh. The present investigation has demonstrated that, in contradistinction to erythrocytes, a normal activity of GSH-Px is found in lymphocytes, granulocytes and platelets of multiple sclerosis patients. Physical activity, psychosocial and perceived environmental factors in adolescents from Northeast Brazil.

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It may bring us a new approach for the resistance, recurrence, and metastasis of tumors. Comparative electrophysiologic evaluation of nerve grafts and autogenous vein grafts as nerve conduits: an experimental study. These results suggest that, relative to their low AS counterparts, female adolescents high in physical concerns respond with elevated anxiety in response to interoceptive arousal and, in turn, endorse elevated coping-related smoking motives.

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First isolation in Puglia of human Yersinia enterocolitica: two cases report. In some cases, the MAPK appears to phosphorylate either the MVQ or the WRKY, while in other cases, both proteins have been reported to act as MAPK substrates.

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Retinas of mice after laser treatment were either light adapted or dark adapted. Nicotine exposure mediklin gel obat jerawat dari increases the complexity of dopamine neurons in the parainterfascicular nucleus (PIF) sub-region of VTA. In small prostates 3 months of hormonal treatment may be enough for maximal volume reduction.

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We sought to investigate whether prenatal vitamin C and E supplementation reduces artose pinner nfl salary caps the incidence of gestational hypertension (GH) and its adverse conditions among high- and low-risk women. These results demonstrate that NO inhibits HASMC proliferation by cGMP-dependent and -independent mechanisms acting at distinct points in the cell cycle.

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Density-functional theory (DFT) for electrons at finite temperature is increasingly important in condensed matter and chemistry. Fifty percent of workers were acivirex suspension exposed to crystalline silica dust in excess of Recommended Exposure Limit -NIOSH and Threshold Limit Value ACGIH (0.025 mg/m(3)). This study was performed in the anesthetized dog to determine if adenosine prevents arterial thrombosis and/or reocclusion after thrombolysis. Four samples were used to extract RNA and generate sequencing libraries, followed by an adapter-driven amplification step, electrophoretic size selection, sequencing, and data analysis. The presence of pain in 1 versus 2 knees provides important information regarding present and future physical functioning.

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Airborne infrared astronomical observations by Fourier losart/hctz 50-12.5 tab sand transform spectroscopy. Pretreatment with 2700 kDa HA resulted in significant suppression of HBFN-f-stimulated NO production in OA and RA cartilages.

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Inflammatory or metabolic markers in blood or tissue were analyzed using immunological or biochemical methods. The study is supporting the project to formulate rightly the proposal of a joint system of managing traumatology cases. Diabetic patients with coronary artery disease have a lower survival and more extensive coronary artery lesions than non cartan brauer hua theorem clinical research diabetic patients with similar age, sex and overall coronary risk. Palliative care is an important and necessary humanistic facet of ICU care. With the presence of fluid adsorption, it is also found that the peak in R(th) is more detectable at low temperature than high temperature.

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Employees were considered to have sickness absence if they reported to be absent at least one day in the past 12 months because of an accident at work, work related problems, or by other health problems. The format of 2D echocardiography is well suited to analyze congenital heart disease, consequences of coronary artery disease, and distortions of anatomy due to acquired heart disease. Polymerization in the presence of templates, followed by their consequent removal, leads to structures with cavities capable of molecular melzap tablets best recognition. These findings suggest that proteins isolated with TRIzol remain amenable to proteomic analyses.

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Due to their high surface area and high, slit-shaped nanoporosity, the synthesized AlOOH nanostructures hold promise for the development of more effective catalysts, adsorbents, vaccines and drug carriers. This article brings the alternative idea of inference to the best explanation to the attention of psychologists and suggests that it provides them with a set protexin pro kolin review of methodological resources for evaluating the explanatory worth of their theories. The objective of this study was to investigate if food intake (dairy, snacks, caloric beverages, bread, cheese, margarine/butter, potato/rice/pasta/grains, red meat, fish and fruit/berries/vegetables) is associated with gestational weight gain (GWG) in Swedish women.